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These success counsel that SB225002 induces p53-dependent apoptosis, and provokes mitotic catastrophe in p53-impartial manner in p53 wild-form cells. Reconstitution with wild-kind P53 in P53-null SKOV3 mobile attenuated SB225002-induced mitotic catastrophe, suggesting p53 prevented mitotic catastrophe induced by SB225002 in p53-deficient OVCA cells. Ultimately, the effect of SB225002 ... https://rachelc196wbf9.activosblog.com/profile

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