Network activity profiles evoked by conolidine and cannabidiol closely matched that of ω-conotoxin CVIE, a potent and selective Cav2.two calcium channel blocker with proposed antinociceptive action suggesting which they way too would block this channel. To confirm this, Cav2.2 channels have been heterologously expressed, recorded with total-cell patch clamp https://elenad493dic4.wikicommunications.com/user