Exogenously administered estrogens are metabolized in exactly the same trend as endogenous estrogens. Metabolic transformation happens largely in the liver and intestine.fifteen Estradiol is metabolized to estrone, and the two are converted to estriol, that is later excreted within the urine. mg drug pre-dissolved in μL DMSO ( Learn liquid https://keeganouzdf.tinyblogging.com/d-pantothenic-acid-for-dummies-71832794