Metabolism Diazepam is N-demethylated by CYP3A4 and 2C19 towards the active metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 to the Lively metabolite temazepam. Hepatic Insufficiency Decreases in clearance and protein binding, and raises in quantity of distribution and 50 %-daily life have been described in patients with cirrhosis. In these https://justpillsdirect.com/product/bensedin-galenika-10mg-diazepam/